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(+)-Magnoflorine iodide

Name: (+)-Magnoflorine iodide
Brand: TargetMol
SKU: T3S1320
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3S1320Cas No. 4277-43-4

Alias Thalictrine iodide, Magnoflorine iodide, Corytuberine Methiodide

(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.

(+)-Magnoflorine iodide

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Purity: 99.59%

Catalog No. T3S1320Alias Thalictrine iodide, Magnoflorine iodide, Corytuberine MethiodideCas No. 4277-43-4

(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$30	In Stock	In Stock
2 mg	$40	In Stock	In Stock
5 mg	$64	In Stock	In Stock
10 mg	$98	In Stock	In Stock
25 mg	$186	In Stock	In Stock
50 mg	$276	In Stock	In Stock
100 mg	$397	In Stock	In Stock
200 mg	$598	-	In Stock
1 mL x 10 mM (in DMSO)	$67	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.59%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

(+)-Magnoflorine iodide AI Summary

(+)-Magnoflorine iodide shows antiplasmodial activity against multi drug-resistant Plasmodium falciparum K1 in erythrocytes, with an IC50 value greater than 107,000.0 nM. Additionally, it exhibits antiamnesic activity against Entamoeba histolytica after 72 hours with an IC50 of 111,000.0 nM. Furthermore, it demonstrates cytotoxicity against human KB cells after 72 hours, with an IC50 value greater than 533,000.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.
Synonyms	Thalictrine iodide, Magnoflorine iodide, Corytuberine Methiodide

Chemical Properties

Molecular Weight	469.31
Formula	C₂₀H₂₄INO₄
Cas No.	4277-43-4
Smiles	[I-].[H][C@@]12Cc3ccc(OC)c(O)c3-c3c(O)c(OC)cc(CC[N+]1(C)C)c23
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (106.54 mM), Sonication is recommended.

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.26 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1308 mL	10.6539 mL	21.3079 mL	106.5394 mL
5 mM	0.4262 mL	2.1308 mL	4.2616 mL	21.3079 mL
10 mM	0.2131 mL	1.0654 mL	2.1308 mL	10.6539 mL
20 mM	0.1065 mL	0.5327 mL	1.0654 mL	5.3270 mL
50 mM	0.0426 mL	0.2131 mL	0.4262 mL	2.1308 mL
100 mM	0.0213 mL	0.1065 mL	0.2131 mL	1.0654 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc